C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/12 (2006.01) A61K 31/517 (2006.01)
Patent
CA 2686221
The present invention provides novel sulfonylurea salts of a salt of formula (I) and polymorph forms thereof. The compounds in their various forms are effective platelet ADP receptor inhibitors and may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also provides a method for preparing such compounds and forms and for preventing or treating thrombosis and thrombosis related conditions in a mammal comprising the step of administering a therapeutically effective amount of a salt of formula (I) or a pharmaceutically acceptable form thereof.
L'invention concerne de nouveaux sels de sulfonylurée d'un sel de formule (I) et leurs formes polymorphes. Les composés sous leurs diverses formes sont des inhibiteurs plaquettaire du récepteur efficaces de l'ADP et peuvent être utilisés dans diverses compositions pharmaceutiques, et sont particulièrement efficaces pour la prévention et/ou le traitement de maladies cardiovasculaires, en particulier celles parmi ces maladies qui ont un rapport avec la thrombose. L'invention concerne également un procédé de préparation de tels composés et de telles formes et de prévention ou de traitement de la thrombose et des états associés à la thrombose chez un mammifère, comprenant l'étape d'administration d'une quantité thérapeutiquement efficace d'un sel de formule (I) ou d'une forme pharmaceutiquement acceptable de celui-ci.
Huang Wolin
Nieder Matthew
Pandey Anjali
Quegan Louisa Jane
Sharp Emma
Fetherstonhaugh & Co.
Portola Pharmaceuticals Inc.
LandOfFree
[4-(6-fluoro-7-methylamino-2,4-dioxo-1,4-dihydro-2h-quinazol... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with [4-(6-fluoro-7-methylamino-2,4-dioxo-1,4-dihydro-2h-quinazol..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and [4-(6-fluoro-7-methylamino-2,4-dioxo-1,4-dihydro-2h-quinazol... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1988990