4,7-dihydrothieno[2,3-b]pyridine derivatives process thereof...

Details 4,7-dihydrothieno[2,3-b]pyridine derivatives process thereof... 4,7-dihydrothieno[2,3-b]pyridine derivatives process thereof...

C - Chemistry, Metallurgy

07

D

167/231, 260/276

C07D 495/04 (2006.01) A61K 31/44 (2006.01)

Patent

CA 1292991

ABSTRACT Highly effective calcium channel blockers having potent antihypertensive and coronary vasodilating actions, ?.?. 4,7- dihydrothieno[2,3-b]pyridine derivatives of the formula: Image wherein R1 is straight or branched chain C1-C4 alkyl, alkoxy- alkyl, or arylalkyl; R2 is hydrogen, straight or branched chain C1-C4 alkyl, or alkoxycarbonyl; R3 is hydrogen, straight or branched chain C1-C4 alkyl, phenyl which may be substituted by one or more halogens or alkoxy groups, optionally substi- tuted cycloalkyl, or optionally substituted cycloalkylalkyl; or R2 and R3 taken together may form an alkylene.

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