4-acylaminophenylacetamidines and a method for their...

Details 4-acylaminophenylacetamidines and a method for their... 4-acylaminophenylacetamidines and a method for their...

A - Human Necessities

61

K

260/544.5

A61K 31/155 (2006.01)

Patent

CA 1037058

4-ACYLAMINOPHENYLACETAMIDINES AND A METHOD FOR THEIR PREPARATION Abstract of the Disclosure New 4-acylaminophenylacetamidines of the formula: Image in which R is a straight or branched chain alkoxyalkyl having 3 to 8 carbon atoms or straight or branched chain alkenyloxyalkyl having 3 to 8 carbon atoms wherein the alkoxy moiety or alkenyl- oxy moiety may substituted by alkoxy or phenyl, and including the non-toxic pharmacologcally acceptable salts thereof. The products have utillty as parasiticides. The products are obtained by either of two methods: (1) via the reaction of an N'-(4-aminophenyl)-N,N-dimethyl- acetamidine with an acylating agent or (2) via the reaction of a 4-acylaminoaniline with an N,N-dimethylacetamide or N,N-dimethylthioacetamide.

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