4-alkyl-thiophenyl-ethanolamines, having an activity on the...

Details 4-alkyl-thiophenyl-ethanolamines, having an activity on the... 4-alkyl-thiophenyl-ethanolamines, having an activity on the...

C - Chemistry, Metallurgy

07

D

260/604, 260/267

C07D 295/00 (2006.01) C07D 295/084 (2006.01) C07D 295/185 (2006.01)

Patent

CA 1215987

ABSTRACT OF THE DISCLOSURE 4-alkyl-thiophenyl-ethanolamines are disclosed, which are compounds having a therapeutical activity against blood-platelet aggregation, and against lipemia and improving the cerebral circulation, said ethanolamines having the general formula: Image wherein R and R1 are alkyl substituents and R2 is a substituent having an amine character. Due to the presence of two asymmetry centres in their molecule, the compounds con- cerned can be prepared in the "threo" and the "erythro" configuration: mixtures of the "threo" and the "erythro" forms have also proven effective.

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