4-amino-2-ureidopyrimidine-5-carboxamides, a process for the...

Details 4-amino-2-ureidopyrimidine-5-carboxamides, a process for the... 4-amino-2-ureidopyrimidine-5-carboxamides, a process for the...

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/505 (2006.01) C07D 233/36 (2006.01) C07D 233/38 (2006.01) C07D 235/02 (2006.01)

Patent

CA 2089954

4-Amino-2-ureidopyrimidine-5-carboxamides, a process for the preparation thereof, pharmaceuticals containing these compounds, and the use thereof Compounds of the formula I (see formula I) in which R1 to R6 have the stated meanings, and the readily water-soluble salts of these compounds, and a process for the preparation thereof era described. The compounds are suitable for the treatment of lipid meta- bolism disorders which era beneficially influenced by a stimulation of the hepatic LDL receptor. Also described are compounds of the formula II (see formula II) and the salts thereof.

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