4-amino-3-acyl quinoline derivatives and their use as...

Details 4-amino-3-acyl quinoline derivatives and their use as... 4-amino-3-acyl quinoline derivatives and their use as...

C - Chemistry, Metallurgy

07

D

C07D 215/44 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2125681

2125681 9312090 PCTABS00022 A compound of formula (I), wherein R1 denotes hydrogen, hydroxyl (OH), halogen or C1-4alkyl, R2 denotes hydrogen or C1-4alkyl, R3 denotes C1-4alkyl, A denotes methylene(-CH2-), ethylene (-CH2CH2-), ethylidene [-CH(CH3)-], trimethylene (-CH2CH2CH2-), oxyethylene (-O-CH2CH2-) or oxytrimethylene (-O-CH2CH2CH2-), X denotes C1-6alkylene or C2-4alkenylene and Y denotes hydroxyl (OH) or amino (NH2), or a salt thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as inhibitors of gastric acid secretion.

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