4-amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidine...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2655754

The invention relates to 4-amino-3-arylamino-6-arylpyrazolo[3,4-d]-pyrimidine derivatives, method for their preparation and their use as antiviral agents. The object was to provide novel compounds which can be employed as agents for example for the treatment of picornavirus infections and which avoid problems of known medicaments, especially relating to resistance and intolerance. This object is achieved by compounds of the general formula I.

L'invention concerne un dérivé de 4-amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidine, son procédé de fabrication et son utilisation en tant qu'agents antiviraux. L'objectif était de développer de nouveaux composés pouvant être utilisés en tant qu'agents actifs, par exemple pour le traitement d'infections aux picornavirus, et évitant les problèmes des médicaments connus, notamment en termes de résistance et d'incompatibilité. Cet objectif est atteint par les composés de formule générale I.

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