C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/281.5
C07D 215/54 (2006.01)
Patent
CA 1147338
379-CIP 4-AMINO-3-QUINOLINECARBOXYLIC ACIDS AND ESTERS- ANTISECRETORY, ANTI-ULCER COMPOUNDS ABSTRACT OF THE DISCLOSURE A method of reducing gastric acidity and treating peptic ulcers and pharmaceutical compositions therefor with certain 4-amino-3-quinolinecarboxylic acids and esters are disclosed. Illustrative of compounds useful in the method which relies on activity as antisecretory activity is the novel compound ethyl 8-methoxy-4-[(2-methylphenyl) amino]-3-quinolinecarboxylate which has the formula: Image
348417
Alphin Reevis S.
Munson Harry R. Jr.
American Home Products Corporation
Smart & Biggar
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