4-amino-6-phenyl-pyrrolo[2,3-d]pyrimidine derivatives

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) C07D 209/00 (2006.01)

Patent

CA 2453881

The invention relates to 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula I wherein the symbols and substituents are as defined in the description, to processes for the preparation thereof, to pharmaceutical compositions comprising such derivatives and to the use of such derivatives-alone or in combination with one or more other pharmaceutically active compounds-for the preparation of pharmaceutical compositions for the treatment especially of a proliferative disease, such as a tumour.

L'invention porte: sur des dérivés de la 7H-pyrrolo[2,3-d]pyrimidine de formule (I) dans laquelle les symboles et les substituants sont tels que définis dans la description, sur leur procédé de préparation, sur des préparations pharmaceutiques les contenant, et sur leur utilisation, seuls ou combinés avec une ou plusieurs composés pharmaceutiquement actifs, en vue de l'élaboration de préparations pharmaceutiques traitant spécialement les maladies prolifératives telles que les tumeurs.

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