4-amino-amphetamine derivatives

Details 4-amino-amphetamine derivatives 4-amino-amphetamine derivatives

C - Chemistry, Metallurgy

07

D

260/283, 260/598

C07D 215/02 (2006.01) C07D 215/06 (2006.01) C07D 215/12 (2006.01) C07D 215/14 (2006.01) C07D 215/18 (2006.01)

Patent

CA 1051436

ABSTRACT OF THE DISCLOSURE This invention relates to a compound of the formula: Image I or a pharmaceutically acceptable salt thereof, in which formula R1 and R2 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R3 represents a lower alkyl group or a benzyl group, R4 represents a hydrogen atom, a lower alkyl group, a benzyl group or a Ch2CH2CH2- bridge connected to the phenyl ring in ortho-position relative to the N-substituent, R5 represents a hydrogen atom or a methyl group and R6 represents a lower alkyl group, provided that R1 and/or R2 represents a lower alkyl group or a halogen atom when R3 represents a methyl group, R4 represents a methyl group and R5 represents a hydrogen atom. The compounds find use as antidepressants.

208356

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