4-amino-n-(4-methyl-4-piperidinyl)-2-methoxybenzamides

Details 4-amino-n-(4-methyl-4-piperidinyl)-2-methoxybenzamides 4-amino-n-(4-methyl-4-piperidinyl)-2-methoxybenzamides

C - Chemistry, Metallurgy

07

D

C07D 211/58 (2006.01) A61K 31/445 (2006.01) C07B 59/00 (2006.01) G01N 33/566 (2006.01) G01N 33/60 (2006.01) A61K 49/02 (1990.01)

Patent

CA 2138150

Piperidinyl substituted benzamides of formula (I) the pharmaceutically acceptable acid addition salts thereof and the stereoisomeric forms thereof, wherein R1 is hydrogen or halo; R2 is halo; R3 is hydrogen or halo; R4 and R5 each independently are hydrogen, C1-4alkyl or haloC1-4alkyl; and the group NR4R5 may also be azido, Alk is C2-4alkanediyl; pharmaceutical compositions containing said compounds of formula (I) as active ingredient; use of said compounds as a medicine; process of preparing said compounds; compounds of formula (I) containing a radioactive isotope; process of marking 5HT2-receptor sites; and process for imaging an organ are disclosed.

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