4-aminoaryldihydropyridine lactones, process for their...

Details 4-aminoaryldihydropyridine lactones, process for their... 4-aminoaryldihydropyridine lactones, process for their...

C - Chemistry, Metallurgy

07

D

167/211, 260/259

C07D 491/048 (2006.01) A61K 31/44 (2006.01) C07D 491/04 (2006.01)

Patent

CA 1300627

23189-6445 ABSTRACT OF THE DISCLOSURE 4 Aminoaryldihydropyridines of the formula Image in which R1 is hydrogen or an organic radical, preferably methyl or ethyl, R2 is hydrogen, C1-C5-alkyl, -CN, -NH2, -CH2 or -CH2OH, preferably methyl, R3 is hydrogen or alkyl, preferably hydrogen Y is -CO- or SO2-, and R4 is an organic radical, or Y-R4 is hydrogen, and physiologically acceptable salts thereof, are circulation- active and effective for improving myocardial contractility, for raising blood pressure, for lowering blood sugar, for reducing mucosal swelling and for controlling the salt and fluid balance. Le A 24 266

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