C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/277, 260/266
C07D 233/90 (2006.01) C07D 233/70 (2006.01) C07D 403/00 (2006.01)
Patent
CA 1175828
ABSTRACT OF THE DISCLOSURE 1,3-Dihydro-2H-imidazol-2-ones having 5-acyl and 4 (substituted amino)methyl substituents, are useful as cardiotonics, antihypertensives and antithrombotic agents. The compounds are obtained by the reaction of an appro- priate amine with a substituted 4-bromomethyl-1,3-di- hydro-2H-imidazol-2-one.
402089
Dage Richard C.
Grisar J. Martin
Schnettler Richard A.
Merrell Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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