4-aminopiperidine derivatives and their use as medicine

Details 4-aminopiperidine derivatives and their use as medicine 4-aminopiperidine derivatives and their use as medicine

C - Chemistry, Metallurgy

07

D

C07D 211/58 (2006.01) A61K 31/445 (2006.01) A61P 5/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2394086

The invention concerns novel 4-aminopiperidine derivatives of formula (I) wherein: R¿1?, R¿2? and R¿3? represent various variable groups, their preparation methods by parallel synthesis processes in liquid and solid phase. Said products have good affinity with certain sub-types of somatostatin receptors, and they are particularly useful for treating pathological conditions or diseases wherein one (or several) somatostatin receptor(s) is/are involved.

La présente demande a pour objet de nouveaux dérivés de 4-aminopipéridines de formule (I) dans laquelle R1, R2 et R3 représentent divers groupes variables, leurs procédés de préparation par des méthodes de synthèse en parallèle en phase liquide et solide. Ces produits ayant une bonne affinité avec certains sous-types de récepteurs de la somatostatine, ils sont particulièrement intéressants pour traiter les états pathologiques ou les maladies dans lesquels un (ou plusieurs) des récepteurs de la somatostatine est (sont) impliqué(s).

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