4-aminotetracyclines and methods of use thereof

Details 4-aminotetracyclines and methods of use thereof 4-aminotetracyclines and methods of use thereof

C - Chemistry, Metallurgy

07

C

C07C 237/26 (2006.01) A61K 31/65 (2006.01) A61P 25/28 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) C07C 239/18 (2006.01)

Patent

CA 2585418

The present invention pertains, at least in part, to novel substituted tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.

L'invention porte, au moins en partie, sur de nouveaux composés tétracycline substituée, qui peuvent être utilisés pour traiter de nombreux états répondant aux composés tétracycline substituée, tels que les infections bactériennes et les néoplasmes, et dans d'autres applications connues des composés tétracycline, par exemple pour bloquer l'efflux de tétracycline et moduler l'expression génique.

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