4-androsten-3-one and process for its production

C - Chemistry – Metallurgy – 07 – J

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C07J 1/00 (2006.01) C07J 31/00 (2006.01) C07J 41/00 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01) C07J 53/00 (2006.01)

Patent

CA 1078826

ABSTRACT OF THE DISCLOSURE The present invention provides compounds of the general formula I (I) Image in which R1 represents a hydrogen atom or an organic or inorganic acid group, R2 represents a hydrogen atom, an alkyl, cycloalkyl or aralkyl group or an organic or inorganic acid group, R3 represents a methyl or ethyl group, R4 represents a hydrogen atom or a methyl group and Image represents Image , Image . Image , Image , Image , Image or Image , R5 represents a lower alkyl group. The compounds of the present invention are, inter alia, diuretics of the type of aldosterone antagonists, that is to say, they reverse the action of desoxycorticosterone on the elimination of sodium and potassium.

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