4-aryl-5,6,7,8-tetrahydropyrazolo(3,4-b)-...

C - Chemistry – Metallurgy – 07 – D

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260/239.5

C07D 487/04 (2006.01) C07D 231/38 (2006.01) C07D 231/40 (2006.01)

Patent

CA 1151645

Abstract of the Disclosure Processes for the preparation of compounds of the formula Image in which R1 and R2 are identical or different and represent hydro- gen atoms or alkyl groups with 1-6 C atoms, it also being possible for one of the radicals R1 and R2 to be, in each case, a benzyl, trifluoromethyl or phenyl group, R3 denotes a hydrogen atom, an alkyl group which has 1-6 C atoms and is optionally substituted by an aryl group, an alkoxy group with 1-6 C atoms, a trifluoro- methyl group, a dialkylamino group with 2-12 C atoms or a cyclo- alkyl group with 3-6 C atoms, an alkenyl or alkynyl group with 2-6 C atoms, a cycloalkyl group with 3-6 C atoms or a carbalkoxy group with 2-6 C atoms, R4 is a hydrogen atom and R5 can be a phenyl group, a phenyl group which is monosubstituted or disubstituted by methyl Cl, Br, F, nitro, cyano and or trifluoro- methyl or a pyridyl group and medicaments containing these compounds. The compounds have anxiolytic and anticonvulsive action and in some cases also an antiphlogistic action.

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