C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/94 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 215/44 (2006.01) C07D 217/22 (2006.01) C07D 239/95 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 471/04 (2006.01) C07D 473/16 (2006.01) C07D 473/34 (2006.01) C07D 475/06 (2006.01)
Patent
CA 2531327
Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
La présente invention concerne des 4-arylamino-quinazolines et des analogues de celles-ci qui sont efficaces en tant qu'activateurs de caspases et d'inducteurs d'apoptose. Les composés selon cette invention sont utilisés pour traiter une variété de pathologies cliniques dans lesquelles interviennent une croissance et un développement incontrôlés de cellules anormales.
Baichwal Vijay
Bhoite Leena
Cai Sui Xiong
Drewe John A.
Jaing Songchun
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Cytovia Inc.
Myriad Genetics Inc.
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