4-arylisoindole analgesics

Details 4-arylisoindole analgesics 4-arylisoindole analgesics

C - Chemistry, Metallurgy

07

D

C07D 209/44 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2179634

The 4-arylisoindoles of formula (I) are effective analgesics including the purified stereoisomers and pharmaceutically acceptable salts thereof, wherein (II) is (III), (IV), (V) or (VI); Rb is hydroxy or C1-5 alkylcarbonyloxy.

4-arylisoindole de formule (I), dans laquelle (II) représente (III), (IV), (V) ou (VI) et R¿b? représente hydroxy ou C¿1-5? alkylcarbonyloxy, ainsi que leurs stéréoisomères purifiés et leurs sels pharmaceutiquement acceptables, s'avèrent des analgésiques efficaces.

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