4-arylmorpholin-3-one derivatives, preparation and...

Details 4-arylmorpholin-3-one derivatives, preparation and... 4-arylmorpholin-3-one derivatives, preparation and...

C - Chemistry, Metallurgy

07

D

C07D 413/06 (2006.01) A61K 31/537 (2006.01) C07D 265/10 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2573446

The invention concerns compounds of formula (I) wherein: Ar represents a mono- or disubstituted phenyl; R1 represents an unsubstituted or substituted phenyl; R2 represents a pyridyl, an unsubstituted or substituted phenyl, an unsubstituted or substituted benzyl on the phenyl; R2 may moreover represent a heterocyclic radical; R3 represents different values. The invention also concerns a method for preparing said derivatives and their therapeutic use.

L1 invention a pour objet des composés répondant à la formule (I) dans laquelle : - Ar représente un phényle mono- ou disubstitué ; - R1 représente un phényle non substitué ou substitué ; - R2 représente : . un pyridyle ; . un phényle non substitué ou substitué ; . un benzyle non substitué ou substitué sur le phényle ; - R2 peut de plus représenter : un radical hétérocyclique ; - R3 représente différentes valeurs. Procédé de préparation et application en thérapeutique.

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