4-aryloxy- and 4-arylthiopiperidine derivatives

Details 4-aryloxy- and 4-arylthiopiperidine derivatives 4-aryloxy- and 4-arylthiopiperidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 413/06 (2006.01) A61K 31/445 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2128380

Novel 4-aryloxy- or 4-arylthiopiperidine derivatives of the formula I (see formula I) in which R1 and R2 are each, independently of one another phenyl radicals which are unsubstituted or mono- or disubstituted by A, OH, OA, aryloxy with 6-10 C atoms, aralkyloxy with 7-11 C atoms, -O,- (CH2)n-O-, Hal, CF3, NO2, NH2, NHA, NA2, NHY, NAY, NHSO2A and/or NASO2A, X is O, S, SO or SO2, m is 1, 2 or 3, n is 1 or 2, A is an alkyl radical with 1-6 C atoms, Hal is F, Cl, Br or I and y is alkanoyl with 1-8 C atoms, aralkanoyl with 1-10 C atoms or aroyl with 7-11 C atoms, and the physiologically acceptable salts thereof, show an effect influencing the central nervous system, in particular neuroleptic effect, with a negligible cataleptic effect.

Affiliated with

Also associated with

Rating

4-aryloxy- and 4-arylthiopiperidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-aryloxy- and 4-arylthiopiperidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-aryloxy- and 4-arylthiopiperidine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1562356