4-aryloxy quinoline derivatives as 5-ht6 modulators

Details 4-aryloxy quinoline derivatives as 5-ht6 modulators 4-aryloxy quinoline derivatives as 5-ht6 modulators

C - Chemistry, Metallurgy

07

D

C07D 215/22 (2006.01) A61K 31/495 (2006.01) A61P 1/00 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2616473

The invention provides compounds of the Formula (I) and pharmaceutically acceptable salts thereof, wherein m, Ar, R1, R2, and R3 are as defined in the specification. The compounds (I) are suitable as 5-HT6 modulators and thus useful in the treatment of certain CNS and gastro intestinal tract disorders.

L'invention porte sur des composés de formule (I), soit: Ar O 2 1 (R ) m R N N N 3 R I 5, et leurs sels pharmacocompatibles, Ar, R1, R2, et R3 étant définis dans la spécification. L'invention porte également sur des méthodes de préparation de compositions et d'utilisation desdits composés.

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