4-aza-19-norandrostane derivatives

Details 4-aza-19-norandrostane derivatives 4-aza-19-norandrostane derivatives

C - Chemistry, Metallurgy

07

J

C07J 73/00 (2006.01) A61K 31/58 (2006.01)

Patent

CA 2210079

Compounds of formula (I) are inhibitors of 5.alpha.-reductase and are useful alone or in combination with other active agents for the treatment of hyperandrogenic disorders such as acne vulgaris, seborrhea, female hirsutism, male pattern baldness, and benign prostatic hyperplasia.

Des composés de la formule (I), qui sont des inhibiteurs de la réductase-5.alpha., ont montré leur efficacité, seuls ou associés à d'autres agents actifs dans le cadre du traitemnt de troubles liés à l'hyperandrogénie tels que l'acné commune, la séborrhée, l'hirsutisme chez la femme, la calvitie hippocratique et l'hyperplasie prostatique bégnine.

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