C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/08 (2006.01) A61K 31/433 (2006.01) A61K 31/437 (2006.01) A61K 31/4427 (2006.01) A61P 3/10 (2006.01) A61P 29/00 (2006.01) C07D 403/08 (2006.01) C07D 405/08 (2006.01) C07D 413/08 (2006.01) C07D 417/08 (2006.01)
Patent
CA 2758929
The present invention comprises compounds of Formula (I). wherein: X, R1, R2, R3, and R4 are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of in-hibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I).
L'invention concerne des composés de formule (I), dans laquelle X, R1, R2, R3, et R4 sont tels que définis dans le descriptif. L'invention concerne également un procédé de prévention, de traitement ou d'amélioration d'un syndrome, d'un trouble ou d'une maladie, le syndrome, le trouble ou la maladie étant le diabète de type II, l'obésité et l'asthme. L'invention concerne également un procédé permettant d'inhiber l'activité de CCR2 chez un mammifère par administration d'une dose thérapeutiquement efficace d'au moins un composé de la formule (I).
Hufnagel Heather Rae
Sui Zhihua
Zhang Xuqing
Janssen Pharmaceutica Nv
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
LandOfFree
4-azetidinyl-1-heteroatom linked-cyclohexane antagonists of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 4-azetidinyl-1-heteroatom linked-cyclohexane antagonists of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-azetidinyl-1-heteroatom linked-cyclohexane antagonists of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1981608