4-benzazonine derivatives and process for preparation thereof

Details 4-benzazonine derivatives and process for preparation thereof 4-benzazonine derivatives and process for preparation thereof

C - Chemistry, Metallurgy

07

D

260/237.3

C07D 225/04 (2006.01) C07D 223/14 (2006.01) C07D 225/06 (2006.01)

Patent

CA 1040628

1. Title of the Invention 4-BENZAZONINE DERIVATIVES AND PROCESS FOR PREPA- RATION THEREOF 2. Abstract of the Disclosure: Novel 4-benzazonine derivatives and their salts, and process for the preparation thereof are disclosed. These 4-benzazonine derivatives are represented by the following general formula: Image wherein R stands for -H, -OH or a lower alkoxy group such as -OCH3, R1 designates -H or a lower alkyl group such as -OH3 and -CH2CH3, R2 indicates -H or a lower alkyl group such as -CH3, R3 stands for -H, a linear or branched, saturated or unsat- urated alkyl group having 1 to 4 carbon atoms, a mono- or di-hydroxy lower alkyl group such as -CH2OH and Image , a saturated cyclic hydro- carbon group having 3 to 6 carbon atoms or a subs- tituted or unsubstituted aromatic hydrocarbon group - 1 - having 6 to 8 carbon atoms, and R4 designates -H, -OH or = 0. These compounds have medicinal effects, especially therapeutical activities to the central nervous system, such as analgesic, antitussive and sedative activities. - 2 -

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