4-benzyl-1-(2h)-phthalazinone derivatives

Details 4-benzyl-1-(2h)-phthalazinone derivatives 4-benzyl-1-(2h)-phthalazinone derivatives

C - Chemistry, Metallurgy

07

D

260/264.3, 260/2

C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 451/04 (2006.01)

Patent

CA 1295613

ABSTRACT OF THE DISCLOSURE 4-Benzyl-1-(2H)-phthalazinone derivatives having antiallergic activity of the formula Image I wherein R1 represents fluorine, chlorine, bromine, tri- fluoromethyl, C1-C6-alkyl, hydroxy, C1-C6-alkoxy, C2-C6-alkanoy- loxy, amino, C1-C6-alkylamino, di-C1-C6-alkylamino, C2-C6-alka- noylamino, C2-C6-alkanoyl-C1-C6-alkylamino or a nitro group, R2 represents hydrogen or has one of the meanings for R1, whereby R1 and R2 may be the same or different, the radicals R3 and R4 are the same or different and represent hydrogen, halogen, C1-C6- alkyl, hydroxy, C1-C6-alkoxy, benzoyloxy or C2-C6-alkanoyloxy and A represent an azacycloalkanyl radical, the aza nitrogen of which contains a C1-C6-alkyl group which is substituted by various rad- icals, and processes for their manufacture.

522580

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