4-benzyl piperidine alkylsulfoxide heterocycles and their...

Details 4-benzyl piperidine alkylsulfoxide heterocycles and their... 4-benzyl piperidine alkylsulfoxide heterocycles and their...

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/198 (2006.01) A61K 31/454 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2327888

Novel 4-Benzyl piperidine alkylsulfoxide heterocycles are disclosed and their use as subtype selective NMDA receptor antagonists, particularly for the treatment of Parkinson's disease, most preferably in combination with L-DOPA.

L'invention concerne de nouveaux hétérocycles de 4-benzyl-pipéridine alkylsulfoxyde et leur utilisation comme antagonistes sélectifs de sous-type du récepteur du NMDA, notamment pour le traitement de la maladie de Parkinson, idéalement en association avec la L-DOPA.

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