4-biphenylacetylene derivatives as anti-inflammatory agents

Details 4-biphenylacetylene derivatives as anti-inflammatory agents 4-biphenylacetylene derivatives as anti-inflammatory agents

C - Chemistry, Metallurgy

07

C

260/653.2, 260/6

C07C 15/50 (2006.01) A61K 31/015 (2006.01) C07C 15/48 (2006.01) C07C 17/18 (2006.01) C07C 17/25 (2006.01) C07C 25/24 (2006.01) C07C 43/215 (2006.01) C07C 45/46 (2006.01) C07C 49/813 (2006.01)

Patent

CA 1158677

ABSTRACT OF THE DISCLOSURE The specification describes novel arylacetylene compounds of the formula I Image I wherein R1 represents hydrogen, chloro, fluoro, methyl or methoxy; and R represents (1) phenyl; (2) substituted phenyl of the formula Image wherein each R2 independently represents hydrogen, chloro, fluoro, or methyl; or (3) cycloalkyl of C5-C7; subject to the limitation that at least one of R1 and R2 is other than hydrogen. They are prepared by halogenating the corresponding acetophenone, and then dehydrohalogenating the resulting ?-halostyrene. Said novel arylacetylene compounds are useful as anti-inflammatory, anti-pyretic, analgesic and anti-thrombotic agents.

216096

Affiliated with

Also associated with

Rating

4-biphenylacetylene derivatives as anti-inflammatory agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-biphenylacetylene derivatives as anti-inflammatory agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-biphenylacetylene derivatives as anti-inflammatory agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1108248