4'-c-ethynyl purine nucleoside compounds

Details 4'-c-ethynyl purine nucleoside compounds 4'-c-ethynyl purine nucleoside compounds

C - Chemistry, Metallurgy

07

H

C07H 19/16 (2006.01) A61K 31/437 (2006.01) A61K 31/7076 (2006.01) A61P 31/18 (2006.01) C07H 19/06 (2006.01) C07H 19/23 (2006.01)

Patent

CA 2308677

The invention provides 4'-C-ethynyl purine nucleosides represented by formula [I]: (see formula I) wherein B represents a base selected from the group consisting of purine and derivatives thereof; X represents a hydrogen atom or a hydroxyl group; and R represents a hydrogen atom or a phosphate residue; and a pharmaceutical composition containing any one of the compounds and a pharmaceutically acceptable carrier. Preferably, the composition is used as an anti-HIV agent or a drug for treating AIDS.

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