4-cyano-2,3,5,6,7,8-hexahydro-3-oxo-isoquinoline compounds

Details 4-cyano-2,3,5,6,7,8-hexahydro-3-oxo-isoquinoline compounds 4-cyano-2,3,5,6,7,8-hexahydro-3-oxo-isoquinoline compounds

C - Chemistry, Metallurgy

07

D

260/288, 260/277

C07D 217/26 (2006.01) C07C 45/45 (2006.01) C07C 49/403 (2006.01) C07C 49/517 (2006.01) C07C 49/657 (2006.01) C07D 213/50 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01)

Patent

CA 1285565

ABSTRACT OF THE DISCLOSURE An isoquinoline derivative of the following formula: Image (I) wherein R1 is a methyl or a methoxymethyl group and R2 and R3 are each a hydrogen atom or a lower alkyl, a lower alkoxyl, a cyclohexyl, a phenyl, a substituted phenyl, a pyridyl or an oxo (= O) group; and therapeutically acceptable salts thereof which exhibit a low toxicity and a wide range of safety and are highly useful as a cardiac.

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