4-cyano-3-hydroxy butanoyl hydrazines, derivatives and...

Details 4-cyano-3-hydroxy butanoyl hydrazines, derivatives and... 4-cyano-3-hydroxy butanoyl hydrazines, derivatives and...

C - Chemistry, Metallurgy

07

C

C07C 243/34 (2006.01) C07C 253/30 (2006.01) C07C 255/20 (2006.01) C07C 255/26 (2006.01)

Patent

CA 2365859

Novel 4-cyano-3-hydroxybutanoyl hydrazides (10), particularlyR-chiral intermediates are described. The intermediates are useful in preparing (R)-3-hydroxy-4-trimethylaminobutyric acid (L-carnitine) and R-4-amino-3-hydroxybutyric acid (GABOB) and chiral chemical intermediates which are medically useful.

Cette invention concerne des 4-cyano-3-hydroxybutanoyl hydrazines (10), et plus particulièrement des intermédiaires R-chiraux. Ces intermédiaires sont utiles dans la préparation de l'acide (R)-3-hydroxy-4-triméthylaminobutyrique (L-carnitine) et de l'acide R-4-amino-3-hydroxybutyrique (GABOB) et d'intermédiaires chimiques chiraux qui conviennent au domaine médical.

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