4-cycloalkyl-substituted tetrahydrochinoline derivatives and...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 215/20 (2006.01) A61K 31/47 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2591397

The invention relates to a novel tetrahydrochinoline derivative, a method for the production thereof, the use thereof either alone in or in combinations for the treatment and/or prevention of illnesses, in addition to the use thereof in the production of medicaments, particularly as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular diseases, particularly hypolipoproteinemias, dyslipidemias, hypertriglyceridemias, hyperlipidemias, hypercholesterolemias and arteriosklerosis.

La présente invention concerne un nouveau dérivé de tétrahydrochinoline, son procédé de production, son utilisation seul ou en association pour traiter et/ou prévenir des maladies ainsi que son utilisation pour produire des médicaments, notamment des inhibiteurs de la cholestérine-Ester-Transfert-Protéine (CETP) pour traiter et/ou prévenir des maladies cardiovasculaires, notamment des hypolipoprotéinémies, dyslipidémies, hypertriglycéridémies, hyperlipidémies, hypercholesterolémies et l'artériosclérose.

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