4-demethoxy-3'-desamino-2'-halo-anthracycline anti- cancer...

Details 4-demethoxy-3'-desamino-2'-halo-anthracycline anti- cancer... 4-demethoxy-3'-desamino-2'-halo-anthracycline anti- cancer...

C - Chemistry, Metallurgy

07

H

260/208.2

C07H 15/252 (2006.01)

Patent

CA 1231942

4-DEMETHOXY-3'-DESAMINO-2'-HALO- ANTHRACYCLINE ANTI-CANCER ANTIBIOTICS Abstract of the Disclosure Compounds of the formula (I), acid addition salts thereof, and pharmaceutical preparations containing the same are disclosed (I) Image wherein R1 is hydroxy; one of X and X' is hydrogen and the other is a halogen atom selected from the group consisting of fluorine, chlorine, bromine, and iodine; one of Y and Y' is hydrogen and the other is selected from the group consisting of hydrogen, hydroxy and -OCOR; one of Z and Z' is hydrogen and the other is hydrogen, hydroxy or -OCOR; and R is a lower alkyl group.

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