4-desacetoxy-4-oxovinblastine

C - Chemistry – Metallurgy – 07 – D

Patent

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260/237.3

C07D 519/04 (2006.01)

Patent

CA 1100957

X-4918-2 -1- ABSTRACT Novel 4-desacetoxy-4-oxoindole-dihydro- indoles which are prepared by the oxidation of the corresponding 4-desacetyl-4.beta.-hydroxyindole-di- hydroindole. They may be reduced to the corre- sponding 4-desacetoxy-4.alpha.-hydroxyindole-dihydro- indoles. 4-Desacetyl-4.alpha.-hydroxyindole-dihydro- indoles and their derivatives thereof, useful as antimitotic agents.

314413

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