4-desacetoxy-4alpha-hydroxyvinblastine and related compounds

Details 4-desacetoxy-4alpha-hydroxyvinblastine and related compounds 4-desacetoxy-4alpha-hydroxyvinblastine and related compounds

C - Chemistry, Metallurgy

07

D

260/237.3

C07D 519/04 (2006.01)

Patent

CA 1100956

X-4785 -1- ABSTRACT Novel 4-desacetoxy-4.alpha.-hydroxyindole- dihydroindoles are prepared by reduction of the corresponding 4-desacetoxy-4-oxoindole-dihydro- indole. 4-Desacetyl-4.alpha.-hydroxyindole-dihydroindoles and their derivatives thereof, useful as antimitotic agents.

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