4-desoxy-epipodophyllotoxin derivative or pharmaceutically...

C - Chemistry – Metallurgy – 07 – D

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C07D 493/04 (2006.01) A61K 31/365 (2006.01) A61K 31/395 (2006.01) A61K 31/695 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2078662

A 4-desoxy-4-epipodophyllotoxin derivative of the following formula (see above formula I) [wherein R and R1 are as defined in the specification] or a pharmaceutically acceptable salt thereof as well as an antitumor composition comprising such derivative or salt as an active ingredient.

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