4-halogeno-2-oxyimino-3-oxobutyric acids

Details 4-halogeno-2-oxyimino-3-oxobutyric acids 4-halogeno-2-oxyimino-3-oxobutyric acids

C - Chemistry, Metallurgy

07

C

260/314, 260/471

C07C 251/32 (2006.01) C07D 233/64 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1295334

Abstract of Disclosure A method of producing a 4-halo-2-(substituted or unsubstituted)hydroxyimino-3-oxobutyric acid ester or amide, which is a synthetic intermediate of value for the production of cephalosporins containing an aminothiazole group, characterized by reacting a 2-(substituted or unsubstituted)- hydroxyimino-3-oxobutyric acid or an ester or amide thereof with a silylating agent and reacting the resulting novel 2- (substituted)hydroxyimino-3-silyloxy-3-butenoic acid ester or amide with a halogenating agent.

537532

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