(?)-4-hydroxy-1,2,9,10-tetraalkoxy-aporphine derivatives

Details (?)-4-hydroxy-1,2,9,10-tetraalkoxy-aporphine derivatives (?)-4-hydroxy-1,2,9,10-tetraalkoxy-aporphine derivatives

C - Chemistry, Metallurgy

07

D

260/282.5

C07D 221/18 (2006.01)

Patent

CA 1077042

A B S T R A C T The new 4-hydroxy-aporphine derivatives according to the present invention are compounds of the general formula: Image (I) wherein R1, R2, R3 and R4, which may be the same or different, are methyl or ethyl radicals, R5 is a hydrogen atom or a straight-chained, cyclic or branched alkyl radical containing up to 5 carbon atoms and the symbol X or Y in the trans- pos- ition to the 6a hydrogen atom represents a hydroxyl group while the remaining X or Y symbol represents a hydrogen atom, with the proviso that when R5 is a methyl radical, then at least one of the substituents R1, R2, R3 or R4 is an ethyl radical. These products useful on the cardiovascular system.

279800

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