4-hydroxy phenylacetic acid

Details 4-hydroxy phenylacetic acid 4-hydroxy phenylacetic acid

C - Chemistry, Metallurgy

07

C

260/516.6

C07C 59/11 (2006.01) C07C 51/367 (2006.01) C07C 51/377 (2006.01)

Patent

CA 1110272

Abstract of the Disclosure 4-Hydroxyphenyl acetic acid is produced by reacting O-chlorophenol with g1yoxylic acid to form 3-chloro-4-hydroxymandelic acid, reducing the 3-chloro-4-hydroxymandelic acid to 3-chloro-4-hydroxyphenyl acetic acid and then dechlorinating the 3-chloro-4-hydroxyphenyl acetic acid to obtain the required 4-hydroxyphenyl acetic acid 4-hydroxyphenyl acetic acid is a useful reagent in the synthesis of many pharmaceutical compounds and the present invention provides a route to the compound by which good yields are obtained.

321909

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