4-(hydroxydiphenylmethyl)-1-piperidylphenylalkane...

Details 4-(hydroxydiphenylmethyl)-1-piperidylphenylalkane... 4-(hydroxydiphenylmethyl)-1-piperidylphenylalkane...

A - Human Necessities

61

K

167/232

A61K 31/445 (2006.01)

Patent

CA 2017573

4-(Hydroxydiphenylmethyl)-1-piperidyl- phenylalkane derivatives as antihistamines of the formula Image and pharmaceutically acceptable salts of such derivatives are disclosed in which n is an integer between 0 and 2, R1 - R5 represent, independently of one another, hydrogen and at least one of them represents a linear or branched alkyl radical with 1 - 4 carbon atoms, a C1-C3-alkoxy radical or a hydroxyl radical. A method of treatment of allergic response in mammals is also disclosed. -17-

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