4-hydroxymethyl-2-pyrrolidinones

Details 4-hydroxymethyl-2-pyrrolidinones 4-hydroxymethyl-2-pyrrolidinones

C - Chemistry, Metallurgy

07

D

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C07D 207/26 (2006.01) C07D 205/04 (2006.01) C07D 307/33 (2006.01)

Patent

CA 1077497

4-HYDROXYMETHYL-2-PYRROLIDINONES ABSTRACT OF THE DISCLOSURE 1-Hydrocarbon-3,3-diphenyl-4-hydroxymethyl-2-pyrrolidinones and methods for making them from 4,5-dihydro-3,3-diphenyl-4- hydrocarbylaminomethylfuran-2(3H)ones are disclosed. Methods for making the 4,5-dihydro-3,3-diphenyl-4-hydrocarbylaminomethylfuran- 2(3H)ones are also disclosed. The novel compounds are useful intermediates for the preparation of pharmacologically active 4-(4,4-disubstitutedpiperidinylmethyl)-3,3-diphenyl-2-pyrrolidinones. -1-

261718

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