4-hydroxytetrahydropyran-2-ones and the corresponding...

Details 4-hydroxytetrahydropyran-2-ones and the corresponding... 4-hydroxytetrahydropyran-2-ones and the corresponding...

C - Chemistry, Metallurgy

07

D

167/244, 167/246

C07D 309/30 (2006.01) A61K 31/215 (2006.01) A61K 31/365 (2006.01) C07C 1/24 (2006.01) C07C 17/12 (2006.01) C07C 17/26 (2006.01) C07C 45/46 (2006.01) C07C 46/04 (2006.01) C07C 50/24 (2006.01) C07C 69/712 (2006.01) C07C 323/20 (2006.01) C07C 323/62 (2006.01) C07C 331/10 (2006.01)

Patent

CA 2024849

-1- 4-Hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, process for their preparation, their use as pharmaceu- ticals, and pharmaceutical preparations and precursors compounds of the formula I Image and the corresponding open-chain dihydroxycarboxylic acids of the formula II Image in which X, Y, R1, R2, R3, R4 and R5 have the meanings indicated, and also their pharmacologically tolerable salts with bases and their pharmacologically tolerable esters, processes for the preparation of these compounds, their use as pharmaceuticals and pharmaceutical prepara- tions are described. In addition, compounds of the formula III Image -2- in which R1, R2, R3, R4, R5, X and Y have the meanings indicated are described.

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