4-imidazolidinones as kv1.5 potassium channel inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 233/36 (2006.01) A61K 31/4166 (2006.01) A61K 31/4439 (2006.01) A61K 31/496 (2006.01) A61P 9/06 (2006.01) C07D 233/32 (2006.01) C07D 233/38 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/08 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 405/04 (2006.01) C07D 405/10 (2006.01) C07D 413/04 (2006.01) C07D 413/10 (2006.01)

Patent

CA 2709186

The present teachings relate to 4-imidazolidinones of Formula (I) Insert formula here as it appears in written form in the specification (I) which are useful as Kv1.5 potassium channel inhibitors providing atrial-selective antiarrhythmic activity. The present teachings further relate to compositions and methods for treating atrial-selective antiarrhythmia.

La présente invention concerne des 4-imidazolidinones selon la Formule (I) insérer ici la formule telle qu'elle est écrite dans la description (I) qui sont utiles en tant qu'inhibiteurs des canaux potassiques Kv1.5 assurant une activité antiarythmique à sélectivité auriculaire. La présente invention a également pour objet des compositions et des procédés de traitement antiarythmique à sélectivité auriculaire.

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