4-imidazoline derivatives

Details 4-imidazoline derivatives 4-imidazoline derivatives

C - Chemistry, Metallurgy

07

D

167/237, 260/314

C07D 233/70 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2014537

- 74 - Abstract of the Disclosure 4-Imidazoline derivatives represented by the formula (I) and/or formula (II): Image Image (I) (II) wherein R1 represents C1-C8 alkyl, C3-C8 alkenyl, C3-C8 alkynyl, C3-C8 cycloalkyl, or optionally substituted aralkyl; R2 and R3 independently represent hydrogen, C3-C20 alkyl, C3-C20 alkenyl, C3-C20 alkynyl, C3-C20 alkoxy, C3-C20 alkenyloxy, C3-C20 alkynyloxy, C3-C8 cycloalkyl, C1-C10 alkylthio, or optionally substituted aralkyl or aralkyloxy; R4 represents C1-C6 alkyl, C3-C8 cycloalkyl, or optionally substituted aralkyl; provided that R2 and R3 cannot be hydrogen at the same time, and pharmaceutically acceptable salts thereof. A pharmaceutical formulation containing the compound is also provided.

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