4-methyl thiazole derivatives, preparation methods therefor...

Details 4-methyl thiazole derivatives, preparation methods therefor... 4-methyl thiazole derivatives, preparation methods therefor...

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01) A61K 31/495 (2006.01) C07D 277/34 (2006.01)

Patent

CA 2075998

Novel 4-methylthiazole derivatives, their methods of preparation and the pharmaceutical compositions in which they are present. ABSTRACT OF THE DISCLOSURE The present invention relates to novel 4- methylthiazole derivatives, to their methods of pre- paration and to the pharmaceutical compositions in which they are present. According to the invention, these derivatives have the general formula Image (I) in which n is equal to 0 or 1 and R1 and R2, which are identical or different, are selected from a hydrogen atom, a halogen, a hydroxyl group, a trifluoromethyl group, an alkyl group having from 1 to 4 carbon atoms and an alkoxy group having from 1 to 5 carbon atoms. Application in the treatment of cardiovascular diseases associated with hyperactivity of the sympa- thetic nervous system.

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