4-(n-substituted amino)-2-butynyl-1-carbamates and...

Details 4-(n-substituted amino)-2-butynyl-1-carbamates and... 4-(n-substituted amino)-2-butynyl-1-carbamates and...

C - Chemistry, Metallurgy

07

C

167/208, 167/249

C07C 271/06 (2006.01) A61K 31/27 (2006.01) A61K 31/395 (2006.01) C07C 271/20 (2006.01) C07C 333/02 (2006.01) C07D 205/04 (2006.01) C07D 295/125 (2006.01) C07D 295/15 (2006.01)

Patent

CA 2022511

ABSTRACT 4-(N-Substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as centrally acting muscarinic agents and are useful as analgesic agents for the treatment of pain, as sleep aids and as agents for treating the symptoms of senile dementia, Alzheimer's disease, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania, or similar conditions of cerebral insufficiency characterized by decreased cerebral acetylcholine production or release.

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