4-(nicotinamidoalkyl)-benzoic acids, the derivatives thereof...

Details 4-(nicotinamidoalkyl)-benzoic acids, the derivatives thereof... 4-(nicotinamidoalkyl)-benzoic acids, the derivatives thereof...

C - Chemistry, Metallurgy

07

D

260/295, 260/294

C07D 213/82 (2006.01) C07D 213/80 (2006.01)

Patent

CA 1113473

Abstract of the disclosure: Benzoic acid derivatives of the formula Image wherein T is hydrogen or halogen, W is a carboxyl group, an ester or salt thereof; X is Image or Image wherein R1 is alkyl having from 2 to 8 carbon atoms, aralkyl or phenyl, cycloalkyl, cycloalkylalkyl or alkylcycloalkyl; R2 is hydrogen or halogen, R3 is alkyl having from 5 to 8 car- bon atoms, aralkyl or phenyl, or cycloalkyl having from 5 to 8 carbon atoms; Y is a single chemical bond or a hydrocarbon chain having from 1 to 3 carbon atoms; Z is hydrogen, halogen, alkyl, alkoxy, alkoxyalkoxy or alkenyloxy, have a blood sugar lowering effect and can be used for the treatment of Diabetes mellitus.

297158

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