4- or 5- substituted pyridine-2-carboxylic acids, a process...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/79 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) C07D 213/80 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2052509

- 1 - HOE 90/F 296 ABSTRACT OF THE DISCLOSURE 4- or 5-substituted pyridine-2-carboylic acids, a process for the preparation thereof and the use thereof as pharmaceuticals The invention relates to pyridine-2-carboxylic acids substituted in position 4 or 5 by carboxyl groups, and to the use thereof as pharmaceuticals. In particular, the action of the compounds for inhibiting proline hydroxylase and lysine hydroxylase and for treating disturbances of the biosynthesis of collagen and collagen-like substances is described.

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