4-oxo-2-ureido-1,4,5,6-tetrahydro-pyrimidine derivatives

Details 4-oxo-2-ureido-1,4,5,6-tetrahydro-pyrimidine derivatives 4-oxo-2-ureido-1,4,5,6-tetrahydro-pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 239/22 (2006.01) A61K 31/505 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 31/55 (2006.01) A61P 31/04 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 455/02 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 475/00 (2006.01) C07D 491/048 (2006.01)

Patent

CA 2328775

The present invention relates to compounds of the formula 1 (see formula I) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein Z, R1, R9, and R10 are as defined herein. The invention also relates to pharmaceutical compositions containing the above compounds and to methods of treating bacterial and protozoal infections in mammals by administering the above compounds.

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