4-oxo-azetidine-2-sulphonic acid amides and their salts,...

Details 4-oxo-azetidine-2-sulphonic acid amides and their salts,... 4-oxo-azetidine-2-sulphonic acid amides and their salts,...

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/395 (2006.01) C07D 205/09 (2006.01) C07D 205/095 (2006.01) C07D 403/12 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2142275

ABSTRACT 4-OXO-AZETIDINE-2-SULFONIC ACID AMIDES AND THEIR SALTS, METHODS FOR THEIR PRODUCTION AND THEIR USE 4-Oxo-azetidine-2-sulfonic acid amides and their salts of the general Formula I Image I in which the radicals have the following meanings: R1 Hydrogen, Halogen R2 Hydrogen, Halogen, NH2, Phenyl-CH2CONH, PhenylOCH2CONH, Phthalimido, o-MeNHCOC6H4CONH, Isoxazolylcarbonylamino; R3 Hydrogen, Me2C=C-COOMe, H2C=C(Me)-CH-COOMe, Me2C=C-COOCH2Phenyl, H2C=C(Me)-CH-COOCH2C6H4NO2-p, Me2C=C-COOCH2C6H4NO2-p, Me2C=C-COOCH2C6H4Me-m, H2C=C(Me)-CHCO-OCH2C6H4Me-m, Me2C=C-COOH; R4 Hydrogen or Sodium, and R5 Hydrogen, Alkyl, Benzyl, or a heterocyclic compound, such as, for instance, Isoxazol, Pyrazol, etc. Method for their production and application as intermediate compounds in the synthesis of beta-Lactam analogs or as active ingredients in the production of preparations for anti-bacterial treatment.

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